20:381.1 Multi Step Tumorigenesis
A 21-minute video from Mark Temple: “1.1 Multi Step Tumorigenesis”.
Mark Temple
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20:38
8:201.2 Polyps of the colon
A 8-minute video from Mark Temple: “1.2 Polyps of the colon”.
11:251.3 A succession of phenotypes
A 11-minute video from Mark Temple: “1.3 A succession of phenotypes”.
12:021.4 Colon cancer pathogenesis - gene mutations
A 12-minute video from Mark Temple: “1.4 Colon cancer pathogenesis - gene mutations”.
7:231.5 Cancer development - clonal selection
A 7-minute video from Mark Temple: “1.5 Cancer development - clonal selection”.
14:241.6 Metastasis and Angiogenesis
A 14-minute video from Mark Temple: “1.6 Metastasis and Angiogenesis”.
10:392.1 Cellular Oncogenes
A 11-minute video from Mark Temple: “2.1 Cellular Oncogenes”.
10:542.2 Mutated DNA causes cellular transformation
A 11-minute video from Mark Temple: “2.2 Mutated DNA causes cellular transformation”.
5:032.3 Many oncogenes have human origin
A 5-minute video from Mark Temple: “2.3 Many oncogenes have human origin”.
7:462.4 Discovery of the H-ras gene
A 8-minute video from Mark Temple: “2.4 Discovery of the H-ras gene”.
8:392.5 The case of Burkitt’s lymphoma
A 9-minute video from Mark Temple: “2.5 The case of Burkitt’s lymphoma”.
6:282.6 Basic cell signalling
A 6-minute video from Mark Temple: “2.6 Basic cell signalling”.
6:502.7 The Src protein
A 7-minute video from Mark Temple: “2.7 The Src protein”.
19:502.8 EGF receptor and the Ras protein
A 20-minute video from Mark Temple: “2.8 EGF receptor and the Ras protein”.
9:463.1 Is Cancer a dominant phenotype
A 10-minute video from Mark Temple: “3.1 Is Cancer a dominant phenotype”.
6:213.2 A new hypothesis – Tumor Suppressor Genes
A 6-minute video from Mark Temple: “3.2 A new hypothesis – Tumor Suppressor Genes”.
7:383.3 Retinoblastoma - a rare childhood eye tumor
A 8-minute video from Mark Temple: “3.3 Retinoblastoma - a rare childhood eye tumor”.
7:293.4 Loss of heterozygosity (LOH)
A 7-minute video from Mark Temple: “3.4 Loss of heterozygosity (LOH)”.
11:593.5 DNA methylation and acetylation
A 12-minute video from Mark Temple: “3.5 DNA methylation and acetylation”.
17:213.6 Control of the Cell Cycle Clock
A 17-minute video from Mark Temple: “3.6 Control of the Cell Cycle Clock”.
15:173.7 pRb and the Cell Cycle
A 15-minute video from Mark Temple: “3.7 pRb and the Cell Cycle”.
9:114.1 Cancer is a disease of uncontrolled cell proliferation
A 9-minute video from Mark Temple: “4.1 Cancer is a disease of uncontrolled cell proliferation”.
12:234.2 Cell Signalling - Immediate Early Genes
A 12-minute video from Mark Temple: “4.2 Cell Signalling - Immediate Early Genes”.
14:344.3 How is ras involved in signaling
A 15-minute video from Mark Temple: “4.3 How is ras involved in signaling”.
14:584.4 Mechanism of receptor tyrosine kinase (RTK) action
A 15-minute video from Mark Temple: “4.4 Mechanism of receptor tyrosine kinase (RTK) action”.
8:024.5 Downstream signalling from Ras (MAPK pathway)
A 8-minute video from Mark Temple: “4.5 Downstream signalling from Ras (MAPK pathway)”.
8:054.6 Downstream signalling from Ras (PI3K pathway)
A 8-minute video from Mark Temple: “4.6 Downstream signalling from Ras (PI3K pathway)”.
7:554.7 Jak-STAT pathway
A 8-minute video from Mark Temple: “4.7 Jak-STAT pathway”.
15:215.1 The Rational Treatment of Cancer
A 15-minute video from Mark Temple: “5.1 The Rational Treatment of Cancer”.
26:485.2 Therapies and accurate diagnosis of cancer
A 27-minute video from Mark Temple: “5.2 Therapies and accurate diagnosis of cancer”.
6:415.3 Anti-cancer drugs - (differentiation and apoptosis)
A 7-minute video from Mark Temple: “5.3 Anti-cancer drugs - (differentiation and apoptosis)”.
13:475.4 Appropriate targets for drug design
A 14-minute video from Mark Temple: “5.4 Appropriate targets for drug design”.
17:445.5 Drugable or undrugable targets
A 18-minute video from Mark Temple: “5.5 Drugable or undrugable targets”.
14:405.6 Drug targets - too many kinases
A 15-minute video from Mark Temple: “5.6 Drug targets - too many kinases”.
5:365.7 Multi-drug resistance
A 6-minute video from Mark Temple: “5.7 Multi-drug resistance”.
8:595.8 Cancer stem cells
A 9-minute video from Mark Temple: “5.8 Cancer stem cells”.